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A “Dognostic” Test

Author: Amna Siddiqui



We all are aware of the fact that dogs have an incredible sense of smell, being used to track down missing people, sniff your luggage at the airport, etc. However, did you know that dogs are capable of detecting cancer? Although the idea was proposed in 1989 for melanomas, the concept is highly fascinating.

In Wisconsin, a woman facing abdominal pain noticed her husky sniffing her belly. After a doctor had denied any thought of serious disease, proclaiming the pain to be ovarian cysts, the woman went to a gynecologist after her dog’s stranger behavior and was diagnosed with stage 3 ovarian cancer. Her dog had effectively diagnosed her cancer by merely smelling it.

This phenomenon is due to dogs’ olfactory (smell) receptors, as they have over 300 million of them, compared to humans, who have about 6 million. So when someone has cancer, a dog can smell the cancer cells or volatile organic compounds. Although dogs are not capable of specifically identifying molecules, they have a general instinct. In ovarian cancer, these compounds are typically detected through body odorants (research is also using blood samples); in lung cancer, these compounds are typically detected through exhaled breath; in prostate cancer, these compounds are typically detected through urine; etc.

Further research has also shown that dogs can smell COVID-19, as portrayed in a study by the University of Pennsylvania’s School of Veterinary Medicine. Several dogs ranging in age were trained to detect COVID in urine samples, reacting to a positive sample.

Although there are several groups training dogs to detect human diseases, like the Medical Detection Dogs in the U.K, the research behind this unique potential still has a long way to go.



Citations:

Note- the phrase “dognostic” was first used in this source: Park, A. (2021, April 15). The dogtor is in: Study finds dogs can sniff out covid-19 with 96% accuracy. Fierce Biotech. Retrieved September 29, 2022, from https://www.fiercebiotech.com/medtech/dogtor-upenn-study-finds-dogs-can-sniff-out-covid-19-96-accuracy#:~:text=A%20new%20study%20led%20by,dognostic%20test%2C%20if%20you%20will.

David L. Chandler | MIT News Office. (n.d.). Toward a disease-sniffing device that rivals a dog's nose. MIT News | Massachusetts Institute of Technology. Retrieved September 29, 2022, from https://news.mit.edu/2021/disease-detection-device-dogs-0217

Lauriello, S. (2020, March 30). Dog detects cancer in owner before doctors-how is that even possible? Health. Retrieved September 29, 2022, from https://www.health.com/condition/ovarian-cancer/dog-detects-owners-cancer-before-doctors#:~:text=Sierra%20the%20Siberian%20Husky%20was,something%20out%20of%20the%20ordinary.

Can animals sniff out cancer? Cancer Council. (n.d.). Retrieved September 29, 2022, from https://www.cancer.org.au/iheard/can-animals-sniff-out-cancer

Campbell, L. F., Farmery, L., George, S. M. C., & Farrant, P. B. J. (2013, October 14). Canine olfactory detection of malignant melanoma. BMJ case reports. Retrieved September 29, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822260/

Can dogs smell cancer? Roswell Park Comprehensive Cancer Center. (n.d.). Retrieved September 29, 2022, from https://www.roswellpark.org/cancertalk/202008/can-dogs-smell-cancer

Academic.oup.com. (n.d.). Retrieved September 29, 2022, from https://academic.oup.com/ejcts/article/52/6/1206/4030727

Robins, M. (2021, August 27). Dogs detecting disease: Meet America's cancer-sniffing canines. American Kennel Club. Retrieved September 29, 2022, from https://www.akc.org/expert-advice/news/meet-americas-cancer-sniffing-canines/

Sniffing out ovarian cancer. PennVet.com. (n.d.). Retrieved September 29, 2022, from https://www.vet.upenn.edu/about/news-room/bellwether/bellwether-magazine/bellwether-fall-2018/sniffing-out-ovarian-cancer

How powerful is a dog's nose? Phoenix Veterinary Center. (n.d.). Retrieved September 29, 2022, from https://phoenixvetcenter.com/blog/214731-how-powerful-is-a-dogs-nose#:~:text=With%20training%2C%20dogs%20can%20sniff,%2C%20malaria%E2%80%94from%20smell%20alone.

Tyson, P. (2012, October 4). Dogs' dazzling sense of smell. PBS. Retrieved September 29, 2022, from https://www.pbs.org/wgbh/nova/article/dogs-sense-of-smell/

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